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Hubble Therapeutics Selects Andelyn to Manufacture Clinical Grade AAV

Andelyn will optimize and scale-up the HUB-101 process, generate GMP-grade plasmids, and produce GMP vectors.

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By: Kristin Brooks

Managing Editor, Contract Pharma

Andelyn Biosciences, Inc., a cell and gene therapy CDMO, has been selected by Hubble Therapeutics to manufacture adeno-associated virus (AAV) using its suspension AAV Curator Platform to manufacture clinical grade AAV for the treatment of Leber Congenital Amaurosis 16 (LCA16)   LCA16 is a severe, early-onset retinal dystrophy resulting from mutations in the KCNJ13 gene, which expresses a critical ion channel in the retinal pigment epithelium cells in the retina. Children typically present with...

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